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Drugmakers have brought almost 450 orphan drugs to market and collected rich incentives by doing so. But nearly a third of the medicines aren't new or were repurposed many times for financial gain.

Spending on campaign ads is up $1 billion from four years ago, according to data from AdImpact, analyzed by NPR. The state that's been the target of the most money is Pennsylvania.

NPR's Leila Fadel talks to Ayman Safadi, Jordan's deputy prime minister and foreign affairs minister, about the risk of an all-out war in Lebanon. Jordan has ties to Israel, Lebanon and the U.S.

It's been a year since a mob supporting former President Donald Trump attacked the U.S. Capitol. We look at what we've learned about domestic extremism over the past year.

The company is introducing a new policy that allows users to appoint an executor who will keep their account active posthumously.

Initial results suggest that Prime Minister Narendra Modi of the BJP party will become prime minister for the third time.

The Defense Department announced Sunday that six men being held at Guantanamo Bay prison have been transferred to Uruguay. NPR's Arun Rath talks to Charlie Savage of the New York Times.

While there were increases in the second quarter of this year, they don't appear to be pushing the growth in health spending toward the painful levels of a decade ago.

Over the weekend, Christopher Pavloski was born. He arrived on Oct. 6, the same date as his father and his grandfather. A BBC statistician puts the odds at 1 in 130,000.

With the Trump-era head of the FDIC stepping down, consumer protection groups see an opportunity to put an end to "rent-a-bank" loans with sky-high interest rates.